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Rare genetic defect replicated in fish model
 

Rare genetic defect replicated in fish model

A rare genetic defect that affects the so-called ALG2 gene can cause serious metabolic diseases in humans. Until now, its rareness and complexity made it difficult to study this congenital glycosylation disorder. A research team has finally succeeded in introducing the underlying mutation in the ALG2 gene in a fish model, allowing the causes of these complex diseases to be studied at the molecular level. ... read more

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